Tufts Institute of Artificial Intelligence and its researchers are leaders in fields such as data science, mathematics, data-driven AI, human-robot interaction, human-AI interaction, human factors engineering, AI in Education, normative AI, Multi-agent systems, and interactive task learning – just to name a few.
We ensure that AI has a meaningful and ethical impact on society through interdisciplinary research projects.
Publications
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- Alqaderi H, Batorsky R, Azar G, Malik MZ, Nizam R, Altabtbaei K, Devarajan S, Ahmad R, Michaud DS, Zhao N, Zavras A, Al-Mulla F. "Comparative machine learning analysis of saliva and plaque microbiomes in Kuwaitis with type 1 diabetes." Front Microbiol. 2026;17:1735375.
- Horng JE, McCrea LT, Batorsky RE, Bowen JJ, Boschian C, Song Y, Perlis RH, Sheridan SD. "Functional genomic profiling of schizophrenia-associated genes reveals key microglial regulators." Neuropsychopharmacology. 2026.
- Alqaderi H, Batorsky R, Azar G, Malik MZ, Nizam R, Altabtbaei K, Devarajan S, Ahmad R, Michaud DS, Zhao N, Zavras A, Al-Mulla F. "Comparative machine learning analysis of saliva and plaque microbiomes in Kuwaitis with type 1 diabetes." Front Microbiol. 2026;17:1735375.
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- Gaikwad, Bipin, Abani Patra, Carl R. Crawford, and Eric L. Miller. "Self-supervised anomaly detection and localization for X-ray cargo images: Generalization to novel anomalies." Engineering Applications of Artificial Intelligence 140 (2025): 109675.
- Georgalis, G., Becerra, A., Budzinski, K., McGurn, M., Faghihi, D., DesJardin, P.E. and Patra, A., 2025. Uncertainty Quantification of Slab Burner Simulation: Surrogates, Forward Propagation, and Parameter Calibration, Journal of Propulsion & Power [Under Review].
- Haensch, A. (2025). Becoming a Data Scientist: An Impractical Guide. The American Mathematical Monthly, 132(1), 6-13.
- McCrea LT, Batorsky RE, Bowen JJ, Yeh H, Thanos JM, Fu T, Perlis RH, Sheridan SD. "Identifying brain-penetrant small-molecule modulators of human microglia using a cellular model of synaptic pruning." Neuropsychopharmacology. 2025;50(10):1544-1552.
- Gaikwad, Bipin, Abani Patra, Carl R. Crawford, and Eric L. Miller. "Self-supervised anomaly detection and localization for X-ray cargo images: Generalization to novel anomalies." Engineering Applications of Artificial Intelligence 140 (2025): 109675.
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- Mitchell Abrams and Christopher Thierauf and Matthias Scheutz (2024). Robots That Perform Norm-Based Reference Resolution. Proceedings of ICSR.
- Ali SA, Perera G, Laird J, Batorsky R, Maron MS, Rivas VN, Stern JA, Harris S, Chin MT. Single Cell Transcriptomic Profiling of MYBPC3-Associated Hypertrophic Cardiomyopathy Across Species Reveals Conservation of Biological Process But Not Gene Expression. J Am Heart Assoc. 2025 Jan 7;14(1):e035780. doi: 10.1161/JAHA.124.035780. Epub 2024 Dec 24. PubMed PMID: 39719426.
- R. M. Aronson, E. Short. "Intentional User Adaptation to Shared Control Assistance". ACM/IEEE International Conference on Human-Robot Interaction (HRI), Boulder, March 2024.
- Batorsky R, Ceasrine AM, Shook LL, Kislal S, Bordt EA, Devlin BA, Perlis RH, Slonim DK, Bilbo SD, Edlow AG. Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity. Cell Rep. 2024;43(6):114326.
- Bourgeois, J. W., Haensch, A., Kher, S., Knox, D., Lanzalotto, G., & Wong, T. A. (2024). How to Use Causal Inference to Study Use of Force. CHANCE, 37(4), 6-10.
- Gaikwad B, Patra A, Crawford C, Miller E (2024). Self-Supervised Anomaly Detection and a New Benchmark for X-Ray Cargo Images. 2024 IEEE International Conference on Image Processing (ICIP).
- J. Huang, R. M. Aronson, E. Short. "Modeling Variation in Human Feedback with User Inputs: An Exploratory Methodology". ACM/IEEE International Conference on Human-Robot Interaction (HRI), Boulder, March 2024.
- J. Huang, I. Sheidlower, R. M. Aronson, E. S. Short. "On the Effect of Robot Errors on Human Teaching Dynamics". International Conference on Human-Agent Interaction (HAI), Swansea, UK, November 2024.
- Jetton D, Muendlein HI, Connolly WM, Magri Z, Smirnova I, Batorsky R, Mecsas J, Degterev A, Poltorak A. Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection. Cell Rep. 2024 Aug 27;43(8):114641. doi: 10.1016/j.celrep.2024.114641. Epub 2024 Aug 17. PubMed PMID: 39154339; PubMed Central PMCID: PMC11465231.
- Joshi VR, Claiborne DT, Pack ML, Power KA, Newman RM, Batorsky R, Bean DJ, Goroff MS, Lingwood D, Seaman MS, Rosenberg E, Allen TM. A VRC13-like bNAb response is associated with complex escape pathways in HIV-1 envelope. J Virol. 2024 Mar 19;98(3):e0172023. doi: 10.1128/jvi.01720-23. Epub 2024 Feb 27. PubMed PMID: 38412036; PubMed Central PMCID: PMC10949433.s
- Pierrick Lorang and Helmut Horvath and Tobias Kietreiber and Patrik Zips and Clemens Heitzinger and Matthias Scheutz (2024). Adapting to the “Open World”: The Utility of Hybrid Hierarchical Reinforcement Learning and Symbolic Planning. Proceedings of ICRA.
- Mirsky, R., & Shpiro, E. (2024, March). Recognition and Identification of Intentional Blocking in Social Navigation. Proceedings of the 2024 International Symposium on Technological Advances in Human-Robot Interaction (pp. 101-110).
- H. Owens, R. M. Aronson, E. Short. "The Limits of Robot Moderators: Evidence Against Robot Personalization and Participation Equalization in a Building Task". IEEE International Conference on Robot and Human Interactive Communication (RO-MAN), Pasadena, August 2024.
- Perera G, Power L, Larson A, Codden CJ, Awata J, Batorsky R, Strathdee D, Chin MT. Single Cell Transcriptomic Analysis in a Mouse Model of Barth Syndrome Reveals Cell-Specific Alterations in Gene Expression and Intercellular Communication. Int J Mol Sci. 2023 Jul 18;24(14). doi: 10.3390/ijms241411594. PubMed PMID: 37511352; PubMed Central PMCID: PMC10380964.
- Retfalvi, K., Georgalis, G., Patra, A. and DesJardin, P.E., 2024. TCP-UQ: two-color pyrometry uncertainty quantification using high speed color cameras. Measurement Science and Technology, 36(1), p.015211.
- M. Scheutz and B. Oosterveld and J. Peterson and E. Wyss (2024). Dialogue-Based Task Instructions and Modifications for Industrial Robots. Proceedings of ARCI 2024.
- M. Scheutz and B. Oosterveld and J. Peterson and E. Wyss and E. Krause (2024). A Multi-Robot Architecture Framework for Effective Robot Teammates in Mixed-Initiative Teams. Proceedings of Technical Advances in Human-Robot Interaction (THARI'24).
- I. Sheidlower, E. Bethel, D. Lilly, R. M. Aronson, E. Short. "Imagining In-distribution States: How Predictable Robot Behavior Can Enable User Control Over Learned Policies". IEEE International Conference on Robot and Human Interactive Communication (RO-MAN), Pasadena, August 2024.
- I. Sheidlower, M. Murdock, E. Bethel, R. M. Aronson, E. Short. "Online Behavior Modification for Expressive User Control of RL-Trained Robots". ACM/IEEE International Conference on Human-Robot Interaction (HRI), Boulder, March 2024.
- J. Staley, S. Goel, Y. Shukla, E. Short. "Agent-Centric Human Demonstrations Train World Models". Reinforcement Learning Conference (RLC), Amherst, August 2024.
- Muhammad Umair and Vasanth Sarathy and JP de Ruiter (2024). Large Language Models Know What To Say But Not When To Speak.
- H. Yu, Q. Fang, S. Fang, R. M. Aronson, E. Short. "How Much Progress Did I Make? An Unexplored Human Feedback Signal for Teaching Robots". IEEE International Conference on Robot and Human Interactive Communication (RO-MAN), Pasadena, August 2024.
- Mitchell Abrams and Christopher Thierauf and Matthias Scheutz (2024). Robots That Perform Norm-Based Reference Resolution. Proceedings of ICSR.
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- Laird J, Perera G, Batorsky R, Wang H, Arkun K, Chin M. Spatial Transcriptomic Analysis of Focal and Normal Areas of Myocyte Disarray in Human Hypertrophic Cardiomyopathy. International Journal of Molecular Sciences. 2023; 24(16). doi: 10.3390/ijms241612625.
- M Dahal, L Kresin, C Rogers (2023). Introductory Activities for Teaching Robotics with SmartMotors. International Conference on Robotics in Education (RiE), 229-241.
- K. H. Allen, A. K. Balaska, R. M. Aronson, C. Rogers, E. Short. "Barriers and Benefits: The Path to Accessible Makerspaces". International ACM SIGACCESS Conference on Computers and Accessibility (ASSETS), New York, October 2023.
- H. Yu, R. M. Aronson, K. H. Allen, E. Short. "From "Thumbs Up" to "10 out of 10": Reconsidering Scalar Feedback in Interactive Reinforcement Learning". International Conference on Intelligent Robots and Systems (IROS), Detroit, October 2023.
- Lyu, Boyang and Nguyen, Thuan and Scheutz, Matthias and Ishwar, Prakash and Aeron, Shuchin. A Principled Approach to Model Validation in Domain Generalization. 2023 IEEE International Conference on Acoustics, Speech, and Signal Processing
- Patrick Feeney and Sarah Schneider and Panagiotis Lymperopoulos and Liping Liu and Matthias Scheutz and Michael C Hughes. NovelCraft: A Dataset for Novelty Detection and Discovery in Open Worlds. Transactions on Machine Learning Research. Transactions on Machine Learning Research (2023).
- Sarah Schneider and Doris Antensteiner and Daniel Soukup and Matthias Scheutz. Encoding Semantic Attributes - Towards Explainable AI in Industry. PETRA '23: Proceedings of the 16th International Conference on PErvasive Technologies Related to Assistive Environments.
- Lyu, Boyang and Nguyen, Thuan and Ishwar, Prakash and Scheutz, Matthias and Aeron, Shuchin. Barycentric-alignment and reconstruction loss minimization for domain generalization. IEEE Access.
- Nguyen, Thuan and Scheutz, Matthias and Aeron, Shuchin. On the failure of Invariant Risk Minimization and an effective fix via classification error control. 2023 IEEE International Workshop on Machine Learning for Signal Processing.
- Christopher Thierauf and Ravenna Thielstrom and Bradley Oosterveld and Will Becker and Matthias Scheutz. "Do this instead"-- Robots that Adequately Respond to Corrected Instructions. ACM Transactions on Human-Robot Interaction (THRI).
- Michael Jahn and Matthias Scheutz. Investigating a Generalization of Probabilistic Material Implication and Bayesian Conditionals. Proceedings of the 39th Conference on Uncertainty in Artificial Intelligence.
- Michael Jahn and Matthias Scheutz. Generalizing Probabilistic Material Implication and Bayesian Conditionals. International Journal of Approximate Reasoning.
- Jennifer Leaf and Julie A. Adams and Matthias Scheutz and Michael A. Goodrich. Resilience for Goal-Based Agents: Formalism, Metrics, and Case Studies. IEEE Access.
- Laird J, Perera G, Batorsky R, Wang H, Arkun K, Chin M. Spatial Transcriptomic Analysis of Focal and Normal Areas of Myocyte Disarray in Human Hypertrophic Cardiomyopathy. International Journal of Molecular Sciences. 2023; 24(16). doi: 10.3390/ijms241612625.
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- I. Sheidlower, A. Moore, E. Short. "Keeping Humans in the Loop: Teaching via Feedback in Continuous Action Space Environments". International Conference on Intelligent Robots and Systems (IROS), Kyoto, October 2022.
- MMA de Graaf, G. Perugia, E. Fosch-Villaronga, A. Lim, F. Broz, E.S. Short. "Inclusive hri: Equity and diversity in design, application, methods, and community". ACM/IEEE Conference on Human-Robot Interaction (HRI), Online, March 2022.
- I. Sheidlower, A. Moore, E. Short. "Keeping Humans in the Loop: Teaching via Feedback in Continuous Action Space Environments". International Conference on Intelligent Robots and Systems (IROS), Kyoto, October 2022.
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- Z Zhang, S Willner-Giwerc, J Sinapov, J Cross, C Rogers (2021). An Interactive Robot Platform for Introducing Reinforcement Learning to K-12 Students. Robotics in Education: RiE 2021 12, 288-301
- Z Zhang, K Lavigne, W Church, J Sinapov, C Rogers (2021). Introducing Reinforcement Learning to K-12 Students with Robots and Augmented Reality. International Conference on Robotics in Education (RiE), 351-365.
- Mirsky, R., Keren, S., & Geib, C. (2021). Introduction to symbolic plan and goal recognition. San Rafael, CA, USA: Morgan & Claypool Publishers. (Vol. 16, pp. 1-190).
- S.Y. Lo, E. Short, A. Thomaz. "Robust Planning with Emergent Human-Like Behavior for Agents Traveling in Groups". International Conference on Robotics and Automation (ICRA), Online, July 2021.
- Z Zhang, S Willner-Giwerc, J Sinapov, J Cross, C Rogers (2021). An Interactive Robot Platform for Introducing Reinforcement Learning to K-12 Students. Robotics in Education: RiE 2021 12, 288-301
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- Vasanth Sarathy, Alexander Tsuetaki, Antonio Roque, Matthias Scheutz (2020). Reasoning Requirements for Indirect Speech Act Interpretation. Proceedings of the 28th International Conference on Computational Linguistics, pages 4937–4948 Barcelona, Spain (Online), December 8-13, 2020.
- Mirsky, R., Macke, W., Wang, A., Yedidsion, H., & Stone, P. (2020). A penny for your thoughts: The value of communication in ad hoc teamwork. International Joint Conference on Artificial Intelligence.
- M. L. Chang, T. K. Faulkner, T. B. Wei, E. S. Short, G. Anandaraman, A. L. Thomaz. "TASC: Teammate Algorithm for Shared Cooperation". IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), Online, October 2020.
- A. D. Allevato, E. S. Short, M. Pryor, A. L. Thomaz. "Iterative residual tuning for system identification and sim-to-real robot learning". Autonomous Robots, Volumn 44, Issue 7, Pages 1167-1182, September 2020.
- M. L. Chang, Z. Pope, E. S. Short, A. L. Thomaz. "Defining Fairness in Human-Robot Teams". IEEE International Conference on Robot and Human Interactive Communication (RO-MAN), Online, 2020.
- T. Kessler Faulkner, E. Short, A. Thomaz. "Interactive Reinforcement Learning with Inaccurate Feedback". International Conference on Robotics and Automation (ICRA), Online, May 2020.
- S.Y. Lo, E. Short, A. Thomaz. "Planning with Partner Uncertainty Modeling for Efficient Information Revealing in Teamwork". ACM/IEEE Conference on Human-Robot Interaction (HRI), Online, March 2020.
- A. Allevato, E. Short, M. Pryor, A. Thomaz. "Learning Labeled Robot Affordance Models by using Simulations and Crowdsourcing". Robotics: Science and Systems (RSS), Online, July 2020.
- Vasanth Sarathy, Alexander Tsuetaki, Antonio Roque, Matthias Scheutz (2020). Reasoning Requirements for Indirect Speech Act Interpretation. Proceedings of the 28th International Conference on Computational Linguistics, pages 4937–4948 Barcelona, Spain (Online), December 8-13, 2020.
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- Vasanth Sarathy, Thomas Arnold, and Matthias Scheutz (2019). When Exceptions Are the Norm: Exploring the Role of Consent in HRI. ACMTransactions on Human-Robot Interaction, Vol. 8, No. 3, Article 14. Publication date: July 2019.
- C. Bethel, M. Bruijnes, M. Jung, C. Mavrogiannis,S. Parsons, C. Pelachaud, R. Prada,L. Riek, S. Strohkorb Sebo, J. Shah, E. Short, M. Vazquez. "Working Group on Social Cognition for Robots and Virtual Agents". Dagstuhl Reports, Volume 9, Issue 10, Seminar on Social Agents for Teamwork and Group Interactions, October 2019.
- A. Allevato, E. Short, M. Pryor, and A. L. Thomaz. “TuneNet: One-Shot Residual Tuning for System Identification and Sim-to-Real Robot Task Transfer”. Conference on Robot Learning (CORL), Osaka, Japan, 2019.
- A. Saran, E. Short, A. L. Thomaz, and S. Niekum. “Understanding Teacher Gaze Patterns for Robot Learning”. Conference on Robot Learning (CORL) , Osaka, Japan, 2019.
- T. Fitzgerald, E. Short, A. Goel, and A. L. Thomaz. “Human-guided Trajectory Adaptation for Tool Transfer”. International Conference on Autonomous Agents and Multiagent Systems (AAMAS) , Montreal, Canada, 2019.
- T. Kessler Faulkner, R. A. Gutierrez, E. Short, G. Hoffman, and A. L. Thomaz. “Active Attention-Modified Policy Shaping”. International Conference on Autonomous Agents and Multiagent Systems (AAMAS) , Mon- treal, Canada, 2019.
- E. Short, A. Allevato, and A. L. Thomaz. “SAIL: Simulation-Informed Active In-the-Wild Learning”. ACM/IEEE Conference on Human-Robot Interaction (HRI) , Daegu, South Korea, 2019.
- Vasanth Sarathy, Thomas Arnold, and Matthias Scheutz (2019). When Exceptions Are the Norm: Exploring the Role of Consent in HRI. ACMTransactions on Human-Robot Interaction, Vol. 8, No. 3, Article 14. Publication date: July 2019.
Grants
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ONR: Effective Novelty-Based Human-Machine Interactions in Open-World Outdoor ISR Domains
Principle Investigator: Matthias Scheutz, Karol Family Applied Technology Professor
The overarching goal of this effort is to reach an unprecedented level of open-world novelty characterization, communication, and adaptation that (1) significantly improves open-world situational awareness and understanding in artificial systems, (2) enables effective human- like communications in open-world settings, and (3) allows agents to quickly adapt their courses of action in the interest of meeting their mission objectives.
AFOSR: Learning and Evaluating Explicit Norms in Human-Machine Teaming Contexts and their Impact on Human Trust
Principle Investigator: Matthias Scheutz, Karol Family Applied Technology Professor
The three overarching objectives of this project are (1) to develop comprehensive formalisms for norms that can represent typical norms used in teaming contexts, together with formal model checking approaches that enable norm compliance checks for a given domain model, (2) to systematically compare “implicit” and “explicit” approaches to norm learning and norm following in simulated single and multi-agent domains with and without human actors, and (3) to determine for the best explicit norm-learning and norm-following approach in human- machine contexts whether artificial agents using it to learn and reason with norms meet human expectations of norm-compliant behavior in different teaming tasks.
DARPA: AIE Friction for Accountability in Conversational Transaction (FACT)
Principle Investigators: Research Assistant Professor Vasanth Sarathy and Karol Family Applied Technology Professor Matthias Scheutz
Current AI systems deployed in complex problem-solving and planning scenarios are standalone programs requiring expert authoring of abstract domain representations. The addition of LLMs as front-ends to these systems enables fluency and reduces friction, but also decreases accountability and potentially engendering overtrust. Broadly, what is missing from these approaches is a conceptual framework for “epistemic vigilance”. We propose using argumentation theory to supply that missing conceptual framework for conversational shaping, specifically representing the chat history as argumentation graphs, which describe relationships between premises, conclusions, and evidence expressed by the interlocutors, and anchored to the domain of discourse. This approach will push the brakes on the conversation to promote critical thinking and epistemic vigilance and prevent overtrust.
DARPA (subcontract to Riverside Research): TEAM-PRO: Teaming Evaluation and Assessment Methodologies for Performance- and Readiness-prediction ObjectivelyPrinciple Investigator: Matthias Scheutz, Karol Family Applied Technology Professor
TEAM PRO addresses key challenges of team performance prediction by incorporating multi-dimensional candidate signatures from cognitive, interpersonal, and physiological domains, reflecting the diverse nature of team dynamics. We tackle the challenge of sparse data, particularly limited ground-truth labels, by augmenting it with simulation data of a teaming scenario like FiST training. This approach generates data motifs in staged scenarios that reveal key teaming challenges, such as communication failures, aiding in identifying predictive signatures. Our use of supplemental Human Subject Research further enables generalization across the program. Employing Large Language Models (LLMs) for automated analysis of team communications provides deep insights and enhanced analytical capabilities, crucial for understanding team interactions, task events, and conversational dynamics.